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Vice President

Tsong-Long Hwang, Ph.D.
Tsong-Long Hwang, Ph.D.

Tsong-Long Hwang, Ph.D.
Tel: 886-3-2118999 ext. 5510
E-Mail: htl@mail.cgust.edu.tw
 

》Current position

Vice President and Distinguished Professor, Chang Gung University of Science and Technology
President, The Society for Free Radical Research-Taiwan
Honorary President, The Society of Chinese Natural Medicine, Taiwan
Jointly Appointed Professor, Ming Chi University of Technology, Taiwan
Jointly Appointed Research Fellow, Chang Gung Memorial Hospital, Taiwan

 

》Professional Experience

2023-Present
Vice President, Chang Gung University of Science and Technology, Taiwan
2015-Present
Dean, College of Human Ecology, Chang Gung University of Science and Technology, Taiwan
2017-Present
Distinguished Professor, Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology
2018-Present
Jointly Appointed Professor, Department of Chemical Engineering, Ming Chi University of Technology, Taiwan
2016-Present
Jointly Appointed Research Fellow, Chang Gung Memorial Hospital, Taoyuan, Taiwan
2015-Present
Professor, Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology
2009-2023
Professor, Graduate Institute of Natural Products, Chang Gung University, Taiwan
2017-2019
Convenor, Division of Pharmacy and Chinese Medicine, Department of Life Sciences, Ministry of Science and Technology, Taiwan
2013-2015
Director, Division of Natural Products, Graduate Institute of Biomedical Sciences, Chang Gung University
2010-2015
Deputy Director, School of Traditional Chinese Medicine, Chang Gung University
2005-2009
Associate Professor, Graduate Institute of Natural Products, Chang Gung University
2000-2005
Assistant Professor, Graduate Institute of Natural Products, Chang Gung University

》Education

1996-2000
Ph.D.
Pharmacology Graduate Institute of Pharmacology, National Taiwan University
1991-1993
M.S.
Pharmacology Graduate Institute of Medicine, Kaohsiung Medical College, Taiwan
1987-1991
B.S.
Pharmacy School of Pharmacy, Kaohsiung Medical College, Taiwan

》Award

2023
Academic Achievement Award from Chang Gung University of Science and Technology
2023
Industry-Academic Cooperation and Development Achievement Award from Chang Gung University of Science and Technology
2022
World's Top 2% Scientists in 2021 and Career (Stanford University) Award from Chang Gung University
2022
World's Top 2% Scientists in 2021 and Career (Stanford University) Award from Chang Gung University of Science and Technology
2022
Invention Silver Award of Taiwan Innotech Expo
2021
Outstanding Research Award from the Society of Chinese Natural Medicine
2021
Excellent Research Award from Chang Gung University
2021
Academic Achievement Award from Chang Gung University of Science and Technology
2021
Industry-Academic Cooperation and Development Achievement Award from Chang Gung University of Science and Technology
2021
Invention Contribution Award of International Inventor Prize from Taiwan International Invention Award Winners Association
2021
World's Top 2% Scientists in 2020 and Career (Stanford University) Award from Chang Gung University
2021
World's Top 2% Scientists in 2020 and Career (Stanford University) Award from Chang Gung University of Science and Technology
2020
Outstanding Inventor Lifetime Achievement Award of International Inventor Prize from Taiwan International Invention Award Winners Association
2020
Invention Gold Award of Taiwan Innotech Expo
2020
Excellent Research Award from Chang Gung University
2019
Wang Ming-Ning Award from Wang Ming-Ning Memorial Foundation
2019
Academic Achievement Award from Chang Gung University of Science and Technology
2018
The 15th National Innovation Award of Taiwan
2018
Academic Achievement Award from Chang Gung University of Science and Technology
2018
Industry-Academic Cooperation and Development Achievement Award from Chang Gung University of Science and Technology
2017
Research and Development Paper Award from Formosa Plastics Group of Taiwan
2016
Academic Achievement Award, Chang Gung University of Science and Technology
2016
Industry-Academic Cooperation and Development Achievement Award, Chang Gung University of Science and Technology
2015
Outstanding Alumni Award, School of Pharmacy, Kaohsiung Medical University
2014
Outstanding Paper Award, The Chinese Society of Immunology, Taiwan
2014
Excellent Teaching Award, Chang Gung University
2007
Wu Ta-You Memorial Award, National Science Council, Taiwan

》Honor and Council Member

2023-Present
Full Member of Sigma Xi: The Scientific Research Honor Society
2019-Present
Honorary President of The Society of Chinese Natural Medicine, Taiwan
2021-2024
President of The Society for Free Radical Research-Taiwan
2020-2024
Director of Taiwan Association for Traditional and Complementary Medicine
2020-2024
Director of The Pharmacological Society in Taiwan
2019-2024
Member of Academic Ethics Committee, Taiwan Food and Drug Administration
2016-2021
Director of The Society for Free Radical Research-Taiwan
2017-2019
Convenor of the Division of Pharmacy and Chinese Medicine, Department of Life Sciences, Ministry of Science and Technology, Taiwan
2017-2019
President of The Society of Chinese Natural Medicine, Taiwan
2014-2016
Director of The Society of Chinese Natural Medicine, Taiwan

》Chief Editor

Frontiers in Natural Products (2022, with the inaugural appointment of Field Chief Editor)

》Editor of SCI Journal

Frontiers in Pharmacology (Associate Editor in Inflammation Pharmacology 2020–present)
Frontiers in Pharmacology (Review Editor in Ethnopharmacology 2020–present)
Scientific Reports (Editorial Board in Chemistry 2015–2016; Immunology 2017–2021; Drug Discovery 2022–present)
Frontiers in Bioscience-Landmark (Editorial Board 2021/02–2023/07)
Marine Drugs (Guest Editor 2017–2018; 2020–2021)
Journal of Geriatric Cardiology (Editorial Board 2014–2021)
International Journal of Pharmacology (Technical Editor 2017–2019)

》Selected Publication

  1. Chen PJ, Tseng HH, Wang YH, Fang SY, Chen SH, Chen CH, Tsai SC, Chang YC, Tsai YF, Hwang TL. Palbociclib blocks neutrophilic phosphatidylinositol 3-kinase activity to alleviate psoriasiform dermatitis. Br J Pharmacol. 2023 Aug;180(16):2172-2188.
  2. Yang SC, Wang YH, Ho CM, Tsai YF, Sung PJ, Lin TE, Hwang TL*. Targeting formyl peptide receptor 1 by anteiso-C13-surfactin for neutrophil-dominant acute respiratory distress syndrome. Br J Pharmacol. 2023 Aug;180(16):2120-2139.
  3. Chen YL, Chen CY, Lai KH, Chang YC, Hwang TL*. Anti-inflammatory and antiviral activities of flavone C-glycosides of Lophatherum gracile for COVID-19. J Funct Foods. 2023 Feb;101:105407.
  4. Lin CY, Yu HP, Chang YT, Lin ZC, Alalaiwe A, Hwang TL*, Fang JY*. Targeting anti-inflammatory immunonanocarriers to human and murine neutrophils via the Ly6 antigen for psoriasiform dermatitis alleviation. Biomater Sci. 2023 Jan 31;11(3):873-893.
  5. Tsai YF, Yang SC, Hsu YH, Chen CY, Chen PJ, Syu YT, Lin CH, Hwang TL*. Carnosic acid inhibits reactive oxygen species-dependent neutrophil extracellular trap formation and ameliorates acute respiratory distress syndrome. Life Sci. 2023 May 15;321:121334.
  6. Wagdy RA, Chen PJ, Hamed MM, Darwish SS, Chen SH, Abadi AH, Abdel-Halim M, Hwang TL*, Engel M*. From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-κB inhibitors. Bioorg Chem. 2022 Oct;127:105977.
  7. Tsai YF, Chen CY, Yang SC, Syu YT, Hwang TL*. Apremilast ameliorates acute respiratory distress syndrome by inhibiting neutrophil-induced oxidative stress. Biomed J. 2022 Sep 11:S2319-4170(22)00135-4.
  8. Lin YJ, Huang CY, Shen YC, Wei KC, Chuang CC, Hsu PW, Huang YC, Hwang TL*, Chen PY*. A manzamine-derived compound as a potential therapeutic agent for glioma by inducing apoptosis and cell cycle arrest. Am J Cancer Res. 2022 Apr 15;12(4):1740-1751.
  9. Kao TI, Chen PJ, Wang YH, Tseng HH, Chang SH, Wu TS, Yang SH, Lee YT, Hwang TL*. Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity. Br J Pharmacol. 2021 Oct;178(20):4069-4084.
  10. Tsai YF, Chen CY, Lin IW, Leu YL, Yang SC, Syu YT, Chen PJ, Hwang TL*. Imperatorin Alleviates Psoriasiform Dermatitis by Blocking Neutrophil Respiratory Burst, Adhesion, and Chemotaxis Through Selective Phosphodiesterase 4 Inhibition. Antioxid Redox Signal. 2021 Oct 10;35(11):885-903.
  11. Korinek M, Hsieh PS, Chen YL, Hsieh PW, Chang SH, Wu YH, Hwang TL*. Randialic acid B and tomentosolic acid block formyl peptide receptor 1 in human neutrophils and attenuate psoriasis-like inflammation in vivo. Biochem Pharmacol. 2021 Aug;190:114596.
  12. Wu YH, Kuo CF, Hsieh AH, Hsieh HL, Chan YF, Hwang TL*. Upregulation of miR-210–5p impairs dead cell clearance by macrophages through the inhibition of Sp1-and HSCARG-dependent NADPH oxidase pathway. Free Radic Biol Med. 2021 Jun 29;172:441-450.
  13. Lin YJ, Wei KC, Chen PY, Lim M*, Hwang TL*. Roles of neutrophils in glioma and brain metastases. Front Immunol. 2021 Aug 13;12:701383. (Review)
  14. Chiang CC, Cheng WJ, Korinek M, Hwang TL*. Targeting Neutrophils to Treat Acute Respiratory Distress Syndrome in Coronavirus Disease. Front Pharmacol. 2020 Oct 9;11:572009. (Review)
  15. Yang SC, Tsai YF, Pan YL, Hwang TL*. Understanding the role of neutrophils in acute respiratory distress syndrome. Biomed J. 2020 Sep 10:S2319-4170(20)30149-9. (Review)
  16. Lu YJ, Wang YH, Sahu RS, Chen JP, Dash BS, Chung PJ, Yang HW, Chuang EY*, Hwang TL*. Mechanism of Nanoformulated Graphene Oxide-Mediated Human Neutrophil Activation. ACS Appl Mater Interfaces. 2020 Sep 9;12(36):40141-40152.
  17. Yang SC, Wang YH, Tsai YF, Chang YW, Wu TS, Ho CM, Hwang TL*. A Synthesized Heterocyclic Chalcone Inhibits Neutrophilic Inflammation Through K + -Dependent pH Regulation. FASEB J. 2020 May;34(5):7127-7143.
  18. Chiang CC, Cheng WJ, Lin CY, Lai KH, Ju SC, Lee C, Yang SH, Hwang TL*. Kan-Lu-Hsiao-Tu-Tan, a Traditional Chinese Medicine Formula, Inhibits Human Neutrophil Activation and Ameliorates Imiquimod-Induced Psoriasis-Like Skin Inflammation. J Ethnopharmacol. 2020 Jan 10;246:112246.
  19. Chen PJ, Ko IL, Lee CL, Hu HC, Chang FR, Wu YC, Leu YL, Wu CC, Lin CY, Pan CY, Tsai YF, Hwang TL*. Targeting allosteric site of AKT by 5,7-dimethoxy-1,4-phenanthrenequinone suppresses neutrophilic inflammation. EBioMedicine. 2019 Feb;40:528-540.
  20. Liu FC, Yu HP, Chen PJ, Yang HW, Chang SH, Tzeng CC, Cheng WJ, Chen YR, Chen YL*, Hwang TL*. A novel NOX2 inhibitor attenuates human neutrophil oxidative stress and ameliorates inflammatory arthritis in mice. Redox Biol. 2019 Jul 10;26:101273.
  21. Tsai YF, Chen CY, Chang WY, Syu YT, Hwang TL*. Resveratrol suppresses neutrophil activation via inhibition of Src family kinases to attenuate lung injury. Free Radic Biol Med. 2019 Dec;145:67-77.
  22. Chen CY, Lee YH, Chang SH, Tsai YF, Fang JY*, Hwang TL*. Oleic acid-loaded nanostructured lipid carrier inhibit neutrophil activities in the presence of albumin and alleviates skin inflammation. Int J Nanomedicine. 2019 Aug 16;14:6539-6553.
  23. Chiang CC, Cheng WJ, Korinek M, Lin CY, Hwang TL*. Neutrophils in Psoriasis. Front Immunol. 2019 Oct 9;10:2376. (Review)
  24. Chen CY, Tsai YF, Huang WJ, Chang SH, Hwang TL*. Propofol inhibits endogenous formyl peptide-induced neutrophil activation and alleviates lung injury. Free Radic Biol Med. 2018 Dec;129:372-382.
  25. Kuo LM, Chen PJ, Sung PJ, Chang YC, Ho CT, Wu YH, Hwang TL*. The bioactive extract of pinnigorgia sp. induces apoptosis of hepatic stellate cells via ROS-ERK/JNK-caspase-3 signaling. Mar Drugs. 2018 Jan;16(1). pii: E19.
  26. Yang SC, Chen PJ, Chang SH, Weng YT, Chang FR, Chang KY, Chen CY, Kao TI, Hwang TL*. Luteolin attenuates neutrophilic oxidative stress and inflammatory arthritis by inhibiting Raf1 activity. Biochem Pharmacol. 2018 Jun 6;154:384-96.

 

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